Lorcaserin General Description

The lorcaserin works by controlling appetite — specifically by activating brain receptors for serotonin, a neurotransmitter that triggers feelings of satiety and satisfaction.Many antidepressant drugs work by preventing the reuptake of serotonin and keeping brain receptors bathed in the chemical.
Intake of food is controlled by satiety center, located in ventromedial nucleus of hypothalamus and hunger center present in lateral hypothalamus.Various inputs from higher centers and gastrointestinal tracts converge in arcuate nucleus, where two types of neurons controlling food intake is present. Firstly, food intake stimulatory group producing agouti-related protein and neuropeptide Y; and secondly, food intake inhibitory group containing cocaine and amphetamine regulated transcript (CART) and pro-opiomelanocortin (POMC) neurons. POMC contains 5-HT 2C receptors, which when activated releases alpha-melanocyte-stimulating hormone (alfa-MSH).Both inhibitory and stimulatory neurons further projects paraventricular nucleus in the hypothalamus.Paraventricular nucleus contains melanocyte 4 receptors (MC4R) that inhibits appetiteIn therapeutic doses lorcaserin acts as a selective 5-HT 2C agonist on POMC neurons, which in turn causes release of alfa MSH. Further alfa MSH acts on MC4R in paraventricular nucleus in the hypothalamus, leading to decrease in appetite. In supratherapeutic doses, lorcaserin also acts on 5-HT 2B and 5-HT 2A receptors.According to clinical trial data submitted by Arena to the FDA, nearly half of dieters without Type 2 diabetes who used the medication lost at least 5% of their starting weight — or an average of 12 lbs. — over a year, compared with 23% of those taking a placebo. For best results, dieters are advised to use the medication together with a healthy diet and exercise program. The approved labeling for Belviq also recommends that people discontinue the drug if they fail to lose 5% of their body weight after 12 weeks; longer treatment is unlikely to lead to meaningful weight loss.Researchers at Arena say their drug is designed to seek out only the serotonin receptors that affect appetite.


What is Tadalafil ?

Tadalafil is a prescription medication that is available on the market under different brand names like Adcirca and Cialis. Also, tadalafil exists in its generic form.Tadalafil is used under different brand names to treat various health conditions. For instance, Cialis is mostly used in the treatment of erectile dysfunction or impotence in men as well as benign prostatic hypertrophy, commonly referred to as an enlarged prostate. On the other hand, Adcirca, which also another tadalafil brand, is used in the treatment of pulmonary arterial hypertension. Adcirca is also used to improve exercise capability in both men and women suffering from pulmonary arterial hypertension.
Tadalafil has the active drug ingredient of Cialis and belongs to a group of medications called phosphodiesterase 5 (PDE5) inhibitors.For ED, Cialis relaxes the blood vessels leading to the penis so that more blood can flow into it. For BPH symptoms, Cialis powder relaxes muscles in your bladder, allowing you to urinate more easily.
Tadalafil powder can treat the following in men
1.witherectile dysfunction (ED), a condition in which you can’t get or keep an erection
2.symptoms of benign prostatic hyperplasia (BPH), a prostate condition that may cause problems with urination ED and symptoms of BPH together
3.Tadalafil powder also successful treatment of Pulmonary Hypertension,and Benign Prostatic Hyperplasia
It’s always advisable to take this drug under your doctor’s guidance to avoid experiencing severe side effects. No matter how you can easily access tadalafil powder don’t take it without undergoing a medical examination.



Orlistat is a gastrointestinal lipase inhibitor that can prevent the absorption of 25% of the fat in the diet. Its role is to prevent the absorption of certain fats in the intestines. Then, the unabsorbed fat is excreted from the feces. When used with a low-calorie and low-fat diet, it can be used for overweight adults aged 18 and over People lose weight. It has the following different brand names: Alli and Xenical.

The prescription drug orlistat is used in overweight people. They may also suffer from high blood pressure, diabetes, high cholesterol, or heart disease. Orlistat can also be used after weight loss to help people avoid weight gain. Orlistat is a class of drugs called lipase inhibitors.


Sesamol, together with its conjugated metabolites, is distributed in body tissues like liver, brain, lungs as well as the kidneys.

When Sesamol is absorbed in the body, it protects DNA from damages and enhances DNA repair to rectify afterγ-radiation damage.

Because of its varied vivo bioactivities, sesamol plays an important role in the treatment of various diseases. One study established that sesamol inhibits the HepG2 cell colony formation. This supports other studies that suggest that Sesamol powder (533-31-3) ruins the viability of the cancer cells.

Normally, the majority of cancer cells need more oxidative stress as compared to the healthy cells in order to maintain the proliferation-apoptosis balance.

Some studies indicate that the interaction of sesamol and DNA is likely to take place at the latter’s groove. Still on that, another research study shows that the cell cycle that has been induced by sesamol arrest at S phase, and this happens in a concentration-dependent way. This is how sesamol causes DNA damage and obstructs the replication of DNA.

Vardenafil Hydrochloride

Vardenafil is a medication that is taken before sexual activity,Vardenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED).  Vardenafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body.vardenafil works by increasing blood flow to the penis to help a man get and keep an erection.

ED or impotence is a condition in which a man is unable to achieve or maintain an erection long enough for sexual intercourse. ifsurgery or radiation to the pelvic area (including prostate, bladder, and rectal procedures), damage can occur to the nerves that supply the penis. and it can take 18-24 months or longer for erectile function to return. These men should be treated aggressively with oral or injectable medications like vardenafil for ED in order to speed recovery of the nerves and to prevent muscle wasting in the penis.

Take vardenafil as directed by your doctor, usually as needed. Take vardenafil, with or without food, about 1 hour before sexual activity. Do not take more than once daily. Doses should be taken at least 24 hours apart.


Avanafil is used to treat erectile dysfunction (ED: impotence; inability to get or keep an erection in men). Avanafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Avanafil does not cure erectile dysfunction or increase sexual desire. Avanafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV,hepatitis B, gonorrhea, syphilis).To decrease your risk of infection, always use an effective barrier method (latex or polyurethane condom/dental dams) during all sexual activity. Consult your doctor or pharmacist for more details.



 No.27 Keyuan Street, Economic Development District, Shanghai County, , 250000

 +86(1368)236 6549





Tadalafil, Orlistat, Lorcaserin hcl powder,Avanafil, Cetilistat,Dapoxetine hcl,Sesamol


JINAN CMOAPI BIOTECHNOLOGY CO., LIMITED. founded in 2007, is a technological enterprise company involved in the research,development and marketing of pharmaceutical raw materials.The company’s mianly products: Lorcaserin, intermediates of Lorcaserin, orlistat,Sesamol,tadalafil and intermediates of tadalafil, etc.
Our factory has comprehensive detection equipment, 60 sets of HPLC, 20 sets of gas chromatographs, LCMS, ELSD, ultraviolet and visible spectrometers, freeze driers and other advanced instruments. It has passed ISO14001, ISO9000 and DMF certification through mergers and acquisitions, and has a total quality management system.

Owner Name:

Dr. Huang

Business Address:

No.27 Keyuan Street, Economic Development District, Shanghai County No.27 Keyuan Street, Economic Development District, Shanghai County

JINAN, Shandong 250000 China

Business Phone:

+86(1368)236 6549

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