- Rosa's Pretzel Bakery
- Roslyn Stationers
- Royal Bank America
- RSF Inc
- Ruba Hall
- Ruffin Nichols Mem AME Ch
- Ruffin Nichols Memorial AME
- Rustica
- S C Nails
- S Hattle Food Corp
- S R & Assoc Ntwrk Resources
- Safemasters Co
- Sage Media
- Saleem's Construction
- Salvation Army
- Sam's Garage
- Samba Enterprises Inc
- Samuel Kravitz & Co
- Sansom Quilting & Embroidery
- Santiago
- SATO
- Save Cleaners
- Sazon Restaurant & Cafe
- SBG Management Svc
- Scharf Investment Group
- SCHOOL Employee's Local 1201
- School Employees Health & Wlfr
- Schuylkill Academy Of Fine Art
- Schwalb Consulting